Can viruses produce insulin-like hormones that can stimulate human cells -- and have potential to cause disease??



Can viruses produce insulin-like hormones that can stimulate human cells -- and have potential to cause disease??

All cell present in human body responds to the hormone insulin secreted by the pancreas, and if that process starts to fail, diabetes occurs due to the increase in the sugar concentration in the body. In a recent, unexpected, finding, scientists   have identified four viruses found in fish that can produce insulin-like hormones that are active on human cells.
The discovery of these  insulin like peptide  producing virus species  propose that micro-organisms have an influence on the advance of diabetes, as well as other major diseases, such as autoimmune diseases and some cancers.

 Experimenting for the first time on mouse and human cells, researchers studied that the VILPs act as hormones and indeed bind to human insulin receptors and receptors for a closely related hormone called IGF-1 (insulin-like growth factor 1). This experiment proves the role of microbes in human disease
These are the critical proteins on the cells that tell them to take up carbohydrate from the cell and to grow.  The peptides could also stimulate all the signalling pathways inside the cells that were stimulated by human insulin and IGF-1. And seen that mice injected with the viral peptides exhibited lower levels of blood glucose, another sign of insulin action. Moreover, analysis of databases of viruses found in the human intestine shows evidence that humans are also exposed to these insulin like hormone producing viruses.
For more details: https://bacteriology.infectiousconferences.com/             

Comments

Post a Comment

Popular posts from this blog

Neisseria gonorrhoeae: Combating a Multidrug-Resistant Organism

Image
Neisseria gonorrhoeae: Combating a Multidrug-Resistant Organism: The worldwide spread of anti-toxin resistant sexually transmitted diseases (STD) has received increased consideration in the course of recent years from health institutes including the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC). In this post we will give a background marked by multidrug-safe Neisseria gonorrhoeae taken after by a depiction of the test techniques clinical labs are utilizing to decide the antimicrobial susceptibilities of N. gonorrhoeae isolates. About Gonorrhea Gonorrhea is a worldwide widespread disease caused by N. gonorrhoeae, a Gram-negative bacterium. As per CDC, roughly 470,000 new gonorrheal diseases were accounted for. Notwithstanding, on the grounds that numerous cases are asymptomatic, and consequently unreported, it is evaluated that there are roughly 820,000 new cases every year. Furthermore, it is assessed that 246,000 of these cases conv...
Read more

How bacteria grow in Anaerobic environment?

Bacteria that grow in Oxygen deficit condition: Scientists have uncovered a mechanism by which bacterial cells in crowded, anaerobic environment access oxygen for energy generation which ensures survival of the cell. The finding could clarify how a few microscopic organisms, for example, Pseudomonas aeruginosa, can flourish in oxygen-poor conditions like biofilms and resist antibiotics. P. aeruginosa biofilm diseases are a main source of death for individuals suffering from cystic fibrosis, a hereditary condition that affects the lungs and the digestive system. Microscopic organisms rarely live by themselves as single-celled organisms. Most rather develop in networks, utilizing the strength of numbers to form a biofilm with tissue-like properties similar to a scaffold that serves to strengthen the community , making it up to 1,000 times more resistant to most antibiotics. Every individual cell should without anyone else extract electrons from food that are then transp...
Read more

The antibiotic that is active against drug-resistant tuberculosis:

Image
The antibiotic that is active against drug-resistant tuberculosis:  A naturally occurring antibiotic called kanglemycin A is effective against Mycobacterium tuberculosis, the bacteria that cause tuberculosis, even in drug-resistant strains, according to an international team of researchers who used chemistry, molecular biology, microbiology, and X-ray crystallography to show how the compound maintains its activity.  The compound, kanglemycin A, is related to the antibiotic rifampicin, according to Katsuhiko Murakami, professor of biochemistry and molecular biology at Penn State and one of leaders of the project. "Rifampicin is already part of the cocktail of antibiotics used to treat tuberculosis, but many strains of the tuberculosis-causing bacteria have developed resistance to it," Murakami said. "Tuberculosis is the leading cause of death by infectious disease worldwide," said Murakami. "Development of rifampicin resistance in M. tuberculosis has m...
Read more