Can viruses produce insulin-like hormones that can stimulate human cells -- and have potential to cause disease??



Can viruses produce insulin-like hormones that can stimulate human cells -- and have potential to cause disease??

All cell present in human body responds to the hormone insulin secreted by the pancreas, and if that process starts to fail, diabetes occurs due to the increase in the sugar concentration in the body. In a recent, unexpected, finding, scientists   have identified four viruses found in fish that can produce insulin-like hormones that are active on human cells.
The discovery of these  insulin like peptide  producing virus species  propose that micro-organisms have an influence on the advance of diabetes, as well as other major diseases, such as autoimmune diseases and some cancers.

 Experimenting for the first time on mouse and human cells, researchers studied that the VILPs act as hormones and indeed bind to human insulin receptors and receptors for a closely related hormone called IGF-1 (insulin-like growth factor 1). This experiment proves the role of microbes in human disease
These are the critical proteins on the cells that tell them to take up carbohydrate from the cell and to grow.  The peptides could also stimulate all the signalling pathways inside the cells that were stimulated by human insulin and IGF-1. And seen that mice injected with the viral peptides exhibited lower levels of blood glucose, another sign of insulin action. Moreover, analysis of databases of viruses found in the human intestine shows evidence that humans are also exposed to these insulin like hormone producing viruses.
For more details: https://bacteriology.infectiousconferences.com/             

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